Genetics account for 20–90% of variability in drug disposition and effects. The rate of drug metabolism varies between individuals. People can be poor, intermediate, extensive or rapid metabolizer of drugs based on their genotype for CYP 450 family of enzymes. CYP 450 family of enzymes metabolized drugs to active or inactive metabolites. People that are poor or rapid metabolizer are prone to drug toxicity or lower effectiveness of drugs.
770,000 injuries and deaths annually in the United States are tied to adverse drug reactions
≈1 in 15 patients will experience an adverse drug reaction
≈1 in 300 patients will have a fatal adverse drug reaction
Our pharmacogenetic testing service, PGx Testing, uses a patient’s genes to determine how they will respond to a particular medicine or a combination of medicines and identifies their unique sensitivities to possible drug effects. As a result, healthcare providers can minimize or completely avoid trial-and-error dosing and substantially reduce the risk of potential adverse drug events.
Our comprehensive report arms physicians with powerful information that helps rank medication choices best suited for a patient, the dosage for efficacy and medications to avoid due to risk for side effects or adverse events.
Physicians frequently utilize PGx testing when a patient has one or more of these issues: