Diabetes and Obesity Genetic Panel

Detect 56 risk factor genes associated with related diseases and syndromes

Alarming statistics report that one in 10 Americans has diabetes, and 90% of those 34 million has type 2 diabetes. Obesity prevalence is equally startling, with the obesity rate of the U.S. population age 20 and older surpassing 40%. If current trends continue, one in three people in the United States will have type 2 diabetes by 2050, and the obesity rate will climb even higher.* While diabetes often goes hand in hand with obesity, the underlying reason for the disease can often be found in a person’s genomic DNA. Diax Lab’s Diabetes and Obesity Genetic Panel specifically tests for genetic types of diabetes.

Diabetes and Obesity Disorders Tested

 Diax Lab’s Diabetes and Obesity Genetic Panel tests for associated forms of diabetes and obesity, including:

  • Type 1 diabetes mellitus (T1DM)
  • Type 2 diabetes mellitus (T2DM)
  • Permanent neonatal diabetes mellitus (PNDM, onset within the first six months of life)
  • Bardet Biedl syndrome (BBS, a rare genetic obesity disease)
  • Prader Willi syndrome (PWS, a complex medical condition)
  • Maturity onset diabetes of the young (MODY) 
  • Alstr m syndrome (a rare genetic disorder affecting organ systems)
  • Wolfram syndrome (a rare genetic endocrine disorder)
  • Renal cysts and diabetes syndrome (MODY 5, maturity-onset diabetes of the young) 
  • Insulin-dependent diabetes mellitus secretory diarrhea syndrome (IPEX, systemic autoimmunity that typically begins in infancy) 
  • Familial partial lipodystrophy (FPL, a genetic disorder of progressive body fat loss)

 

The Extensive Benefits of Genetic Testing

Although there’s no cure for diabetes and obesity disorders, there are many advantages to understanding a patient’s genetic risk factors.

Diax Lab’s Diabetes and Obesity Genetic Panel can: 

  • Detect potential underlying genetic causes for diabetes
  • Provide or lead to an accurate diagnosis

As a result, the patient can:  

  • Gain insight into potential risks and conditions  
  • Make timely lifestyle adjustments  
  • Seek necessary treatment to minimize long-term complications  
  • Share risk factors with family members who might have the same genetic variant
  • Participate in clinical trials  
  • Obtain gene therapy, if available  
  • Explore options for family planning and embryo selection

And the physician can:  

  • Personalize a patient’s treatment plan  
  • Connect the patient with relevant resources and support

Who Should Be Tested?

Our Diabetes and Obesity Genetic Panel is uniquely designed for patients who have symptoms associated with diabetes, an obesity disorder and/or a family history of diabetes. Results from the test will provide valuable information for family members – siblings, parents, children – of patients who have a genetic variant for diabetes or obesity disorders.

Beyond the Test

The importance of an accurate, timely diagnosis cannot be overstated. 

  • Diabetes impacts many parts of the body beyond blood: eyes, kidneys, nerves, heart and blood vessels, feet and gums. 

  • The risk factors associated with diabetes are also risk factors for other serious chronic conditions and diseases, including sleep apnea, dementia, bacterial and fungal infections, stroke, heart disease and high blood pressure. 

  • An accurate diagnosis allows a patient to address a wide range of environmental factors, including nutrition and physical activity affecting health and health behavior. 

  • A diagnosis is also important to family members who might be at similar risk of having inherited the same genetic variant and make necessary lifestyle changes to delay the onset of diabetes. 

 * Centers for Disease Control and Prevention

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